期刊简介
中华医学会主办。本刊是国内烧伤学术界惟一的全国性权威刊物，由国内外烧伤外科及相关学科著名专家组成编委会。烧伤的重要问题，通常也是内外科的基本问题。杂志力求充分展示本学科领域的新理论、新技术、新方法、新经验，注重实用性，讲究可读性。全方位展示本专业的研究进展、临床治疗和护理经验，将整形与康复理念贯穿于烧伤救治全过程，将独到的修复技术应用于各种类型的难治性创面。杂志目前已被《Medline》等10多个国际主要数据库收录，具有较大影响。
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首页>中华烧伤杂志
- 杂志名称：中华烧伤杂志
- 主管单位：中国科学技术协会
- 主办单位：中华医学会
- 国际刊号：1009-2587
- 国内刊号：50-1120/R
- 出版周期：月刊
期刊荣誉：中华医学会优秀期刊三等奖期刊收录：文摘与引文数据库, 万方收录(中), 医学文摘, CSCD 中国科学引文数据库来源期刊(含扩展版), 国家图书馆馆藏, 知网收录(中), 维普收录(中), CA 化学文摘(美), 上海图书馆馆藏, 北大核心期刊(中国人文社会科学核心期刊), 统计源核心期刊(中国科技论文核心期刊), JST 日本科学技术振兴机构数据库(日), 哥白尼索引(波兰)
脓毒症免疫功能障碍机制及血必净调节效应研究进展
高玉雷；柴艳芬；姚咏明
关键词：免疫, 脓毒症, 血必净注射液, 治疗
摘要：Sepsis is a systemic inflammatory response syndrome resulting from a host response to infection.The early stage of sepsis is characterized by excessive inflammatory response,accompanied by immune dysfunction characterized by aggravating cellular immunosuppression.The vast majority of patients with sepsis survive the initial excessive inflammatory response,but die of hospital-acquired infection,opportunistic pathogenic bacteria infection,latent virus reactivation,and multiple organ dysfunction syndrome.These facts indicate that immunosuppression may be a significant cause of exacerbation of the illness even death of the septic patients.The primary cellular mechanisms in inducing immune dysfunction include immune dysfunction of T lymphocytes,negative regulation of regulatory T lymphocytes and dendritic cells,and damage of intestinal mucosa associated lymphoid tissue.Xuebijing injection is a complex Chinese patent medicine,which is widely used in the treatment of sepsis.It has a potential immunoregulation ability,as well as effects on bacteriostasis,anti-endotoxin and anti-inflammation.Its target and mechanism of action need to be explored further.
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